Granule cell dispersion is restricted across transverse boundaries in mouse chimeras

  title={Granule cell dispersion is restricted across transverse boundaries in mouse chimeras},
  author={R. Hawkes and E. Beierbach and S. S. Tan},
  journal={European Journal of Neuroscience},
  • R. Hawkes, E. Beierbach, S. S. Tan
  • Published 1999
  • Biology, Medicine
  • European Journal of Neuroscience
  • The granular layer of the developing and adult cerebellum is marked by the presence of several transverse boundaries, revealed in gene expression patterns or as a consequence of genetic mutations. It is unclear whether these boundaries represent fundamental differences between granule cell populations or if they are a secondary response to regional differences in the underlying Purkinje cells. One possibility is that boundaries mark different spatial domains of granule cells in a lineage… CONTINUE READING
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