Granisetron plus alprazolam versus granisetron alone in the control of emesis in patients with operable breast cancer receiving anthracycline containing chemotherapy: A phase III trial.

Abstract

8081 Background: Even with optimal antiemetic treatment, about only 20% of patients are completely free from nausea and vomiting (NV). Benzodiazepines have been previously shown to be useful in the prophylaxis of NV. Alprazolam, a newer benzodiazepine, has antidepressant effect and may be useful in NV control. METHODS Nineteen operable breast cancer… (More)

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