Gramicidins A, B, and C form structurally equivalent ion channels.

  title={Gramicidins A, B, and C form structurally equivalent ion channels.},
  author={D B Sawyer and L P Williams and W. L. Whaley and Roger E Koeppe and Olaf S Andersen},
  journal={Biophysical journal},
  volume={58 5},
The membrane structure of the naturally occurring gramicidins A, B, and C was investigated using circular dichroism (CD) spectroscopy and single-channel recording techniques. All three gramicidins form channels with fairly similar properties (Bamberg, E., K. Noda, E. Gross, and P. Läuger. 1976. Biochim. Biophys. Acta. 419:223-228.). When incorporated into lysophosphatidylcholine micelles, however, the CD spectrum of gramicidin B is different from that of gramicidin A or C (cf. Prasad, K. U., T… CONTINUE READING