Gram Negative Bacteria Are Associated with the Early Stages of Necrotizing Enterocolitis

@inproceedings{Carlisle2011GramNB,
  title={Gram Negative Bacteria Are Associated with the Early Stages of Necrotizing Enterocolitis},
  author={Erica M. Carlisle and Valeriy A. Poroyko and Michael S. Caplan and John A. Alverdy and Donald C. Liu},
  booktitle={PloS one},
  year={2011}
}
INTRODUCTION Necrotizing enterocolitis (NEC) affects 5-10% of infants born weighing less than 1500 g. Most models of NEC recapitulate late-stage disease with gut necrosis and elevated inflammatory mediators. Evaluation of NEC at earlier, less lethal stages of disease will allow investigation of initial disease triggers and may advance our understanding of temporal relationships between factors implicated in NEC pathogenesis. In this manuscript, we describe our investigation of early NEC and… CONTINUE READING