Grafts of meningeal fibroblasts in adult rat spinal cord lesion promote axonal regrowth.

@article{Franzen1999GraftsOM,
  title={Grafts of meningeal fibroblasts in adult rat spinal cord lesion promote axonal regrowth.},
  author={Rachelle Franzen and D Zachary Martin and A Daloze and Gustave Moonen and Jean Schoenen},
  journal={Neuroreport},
  year={1999},
  volume={10 7},
  pages={1551-6}
}
We have studied the morphological consequences of implantation into the injured adult rat spinal cord of fibroblasts derived from the meninges overlying the cerebral cortex. Our initial objective was to reproduce the well known post-traumatic fibroadhesive scar observed in the clinical situation. One month after implantation, instead of having formed a fibroadhesive scar, fibroblasts had promoted the regeneration of peptidergic axons originating from dorsal root afferents and, to a lesser… CONTINUE READING

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