Graft-versus-leukemia effect of donor lymphocyte transfusions in marrow grafted patients.

@article{Kolb1995GraftversusleukemiaEO,
  title={Graft-versus-leukemia effect of donor lymphocyte transfusions in marrow grafted patients.},
  author={H. J. Kolb and A. Schattenberg and John M. Goldman and Bernd Hertenstein and Nina Jacobsen and William Arcese and Per Ljungman and Augustin Ferrant and Ludo Verdonck and Dieter Niederwieser and Frits van Rhee and Johann Mitterm{\"u}ller and Theo de Witte and Ernst Holler and H. Ansari},
  journal={Blood},
  year={1995},
  volume={86 5},
  pages={2041-50}
}
The immune reactivity of allogeneic lymphocytes plays a major role in the control of leukemia after bone marrow transplantation. In patients with recurrent leukemia after marrow transplantation, chimerism and tolerance provide ideal conditions for adoptive immunotherapy with donor lymphocytes. We studied the effect of donor lymphocyte transfusions on acute and chronic leukemia in relapse after bone marrow transplantation. One hundred thirty-five patients with chronic myeloid leukemia (CML) (N… CONTINUE READING
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