Graft site and gonadotrophin stimulation influences the number and quality of oocytes from murine ovarian tissue grafts.

@article{Yang2006GraftSA,
  title={Graft site and gonadotrophin stimulation influences the number and quality of oocytes from murine ovarian tissue grafts.},
  author={Hsiao Yun Yang and Shae-Lee Cox and Graham Jenkin and Jock K. Findlay and Alan Trounson and Jillian Shaw},
  journal={Reproduction},
  year={2006},
  volume={131 5},
  pages={851-9}
}
Ovarian tissue cryopreservation and subsequent transplantation can restore fertility in cancer patients. This study used a mouse ovarian grafting model to investigate whether the graft site (bursal cavity, the kidney capsule or subcutaneous) influences the number, fertilization rate and developmental potential of oocytes recovered from grafts and whether using a standard gonadotrophin stimulation protocol would increase oocyte yield from the grafts. Mouse ovarian tissue was grafted into four… CONTINUE READING

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