Graft failure in patients receiving T cell-depleted HLA-identical allogeneic marrow transplants.

@article{Martin1988GraftFI,
  title={Graft failure in patients receiving T cell-depleted HLA-identical allogeneic marrow transplants.},
  author={Paul J Martin and John A Hansen and Beverly J Torok-Storb and Diane M. Durnam and Donna Przepiorka and John O'Quigley and Jean Sanders and Keith M. Sullivan and Robert P. Witherspoon and H. Joachim Deeg},
  journal={Bone marrow transplantation},
  year={1988},
  volume={3 5},
  pages={445-56}
}
Results of a previous study suggested that the risk of graft failure after transplantation of HLA-identical T cell-depleted marrow may be influenced by the preparative regimen. Subsequent clinical trials were carried out to clarify this relationship and to determine whether post-transplant immunosuppression could have an effect on graft durability. Two factors were found to be associated with graft failure. Patients with hematologic malignancy given a preparative regimen of cyclophosphamide… CONTINUE READING