Gradual loss of synaptic cartels precedes axon withdrawal at developing neuromuscular junctions.

Abstract

We have studied the spatial deployment of synapses arising from different axons that converge on the same developing neuromuscular junctions. Labeling the competing synaptic "cartels" with different dyes in mouse muscle showed that, perinatally, each axon adds similar terminal areas, whereas later, areas occupied by the competing cartels diverged by gradual… (More)

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