Gradual development of a genome-wide H3-K9 trimethylation pattern in paternally derived pig pronucleus.

Abstract

The cytoplasm of a mature oocyte contains many protein complexes that are programmed to restructure incoming sperm chromatins on fertilization. Of the complicated biochemical events that these functional machineries control, the most impressive and important is epigenetic reprogramming. Despite its importance in epigenetic resetting, or "de-differentiation… (More)

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