Gradients During Excitation-Contraction Coupling in Newborn Rabbit Ventricular Myocytes

@inproceedings{Haddock1999GradientsDE,
  title={Gradients During Excitation-Contraction Coupling in Newborn Rabbit Ventricular Myocytes},
  author={Peter S. Haddock and William A Coetzee and Emily Cho and Lisa J. Porter and Hideki Katoh and Donald M. Bers and Mohsin Saleet Jafri and Michael Artman},
  year={1999}
}
The central role of T-tubule and sarcoplasmic reticulum (SR) diadic junctions in excitation-contraction (EC) coupling in adult (AD) ventricular myocytes suggests that their absence in newborn (NB) cells may manifest as an altered EC coupling phenotype. We used confocal microscopy to compare fluo-3 [Ca ]i transients in the subsarcolemmal space and cell center of field-stimulated NB and AD rabbit ventricular myocytes. Peak systolic [Ca ]i occurred sooner and was higher in the subsarcolemmal space… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 37 REFERENCES

Immunolocalization of dihydropyri - dine and ryanodine receptors in developing rabbit cardiomyocytes using 3 D microscopy

  • F Sedarat, ED Moore, GF Tibbits
  • Biophys J
  • 1999

Immunolocalization of dihydropyridine and ryanodine receptors in developing rabbit cardiomyocytes using 3D microscopy.Biophys

  • F Sedarat, ED Moore, GF. Tibbits
  • J. ;76:A306. Abstract
  • 1999

Subcellular distribution of triadin and the ryanodine receptor (RYR) in developing cardiac sarcoplasmic reticulum (SR)

  • S Parameswaran, L Jones, Y Kobayashi, O. Jorgensen
  • Biophys J. ;76:A469. Abstract
  • 1999

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