Gradient-Domain Processing for Large EM Image Stacks

  title={Gradient-Domain Processing for Large EM Image Stacks},
  author={Michael M. Kazhdan and Randal C. Burns and Bobby Kasthuri and Jeff Lichtman and R. Jacob Vogelstein and Joshua T. Vogelstein},
We propose a new gradient-domain technique for processing registered EM image stacks to remove the inter-image discontinuities while preserving intra-image detail. To this end, we process the image stack by first performing anisotropic diffusion to smooth the data along the slice axis and then solving a screened-Poisson equation within each slice to re-introduce the detail. The final image stack is both continuous across the slice axis (facilitating the tracking of information between slices… CONTINUE READING
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