Graded boosting of synaptic signals by low-threshold voltage-activated calcium conductance.

  title={Graded boosting of synaptic signals by low-threshold voltage-activated calcium conductance.},
  author={Mart{\'i}n Carb{\'o} Tano and Mar{\'i}a Eugenia Vilarchao and Lidia Szczupak},
  journal={Journal of neurophysiology},
  volume={114 1},
Low-threshold voltage-activated calcium conductances (LT-VACCs) play a substantial role in shaping the electrophysiological attributes of neurites. We have investigated how these conductances affect synaptic integration in a premotor nonspiking (NS) neuron of the leech nervous system. These cells exhibit an extensive neuritic tree, do not fire Na(+)-dependent spikes, but express an LT-VACC that was sensitive to 250 μM Ni(2+) and 100 μM NNC 55-0396 (NNC). NS neurons responded to excitation of… CONTINUE READING
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