Gq/11-induced and spontaneous waves of coordinated network activation in developing frontal cortex.

@article{Calderon2005Gq11inducedAS,
  title={Gq/11-induced and spontaneous waves of coordinated network activation in developing frontal cortex.},
  author={Diany Paola Calderon and Natalya Leverkova and Alejandro Peinado},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2005},
  volume={25 7},
  pages={1737-49}
}
Repeated episodes of spontaneous large-scale neuronal bursting and calcium influx in the developing brain can potentially affect such fundamental processes as circuit formation and gene expression. Between postnatal day 3 (P3) and P7, the immature cortex can express one such form of activation whereby a wave of neuronal activity propagates through cortical networks, generating massive calcium influx. We previously showed that this activity could be triggered by brief stimulation of muscarinic… CONTINUE READING

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