Gpr124 is essential for blood–brain barrier integrity in central nervous system disease


Although blood–brain barrier (BBB) compromise is central to the etiology of diverse central nervous system (CNS) disorders, endothelial receptor proteins that control BBB function are poorly defined. The endothelial G-protein-coupled receptor (GPCR) Gpr124 has been reported to be required for normal forebrain angiogenesis and BBB function in mouse embryos… (More)
DOI: 10.1038/nm.4309


5 Figures and Tables