Gp130 and the interleukin-6 family of cytokines.

@article{Taga1997Gp130AT,
  title={Gp130 and the interleukin-6 family of cytokines.},
  author={T. Taga and T. Kishimoto},
  journal={Annual review of immunology},
  year={1997},
  volume={15},
  pages={
          797-819
        }
}
Receptors for most interleukins and cytokines that regulate immune and hematopoietic systems belong to the class I cytokine receptor family. These molecules form multichain receptor complexes in order to exhibit high-affinity binding to, and mediate biological functions of, their respective cytokines. In most cases, these functional receptor complexes share common signal transducing receptor components that are also in the class I cytokine receptor family, i.e. gp130, common beta, and common… Expand
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