Environmental factors and risk of gout.
- Environmental ScienceEnvironmental research
Effect of fenofibrate on uric acid level in patients with gout
- Medicine, BiologyScientific Reports
Fenofibrate additionally reduced uric acid levels without showing any change in the results of renal or liver function tests, suggesting that the addition of fen ofibrate is a reasonable option for treating gout in patients having high triglyceride levels.
Non-steroidal anti-inflammatory drugs for acute gout.
- MedicineThe Cochrane database of systematic reviews
This update of a Cochrane Review of non-steroidal anti-inflammatory drugs (NSAIDs) for acute gout finds low-certainty evidence (downgraded for bias and imprecision) from 1 trial (30 participants) shows NSAIDs compared to placebo, and indicates non-selective NSAIDs may have little to no effect on inflammation.
The Role of the Intestine in the Development of Hyperuricemia
- Medicine, BiologyFrontiers in Immunology
The effects of intestinal uric Acid transporters and intestinal flora on uric acid excretion are reviewed, and new ideas for the treatment of hyperuricemia and gout are provided.
Anti-gout Medications and Risk of Cardiovascular Disease: A Nested Case-Control Study
- MedicineFrontiers in Medicine
Gout patients taking ULT (allopurinol and benzbromarone) with an adherence rate of ≥0.7 are at a lower risk of developing CVD, especially with a younger age (<65) and if they are male, and the benefit is more pronounced in ischemic heart disease.
Hyperuricemia: a novel old disorder—relationship and potential mechanisms in heart failure
- Medicine, BiologyHeart Failure Reviews
The effects of lowering plasma uric acid concentration on the prognosis of heart failure is discussed by reviewing most of available data on the different classes of drugs directly or indirectly involved in the hyperuricemia management.
Traditional Chinese medicine for gouty arthritis
The findings of the study will provide helpful evidence for the efficacy and safety of simiao powder combined with acupuncture in the treatment of GA.
IL-17A neutralizing antibody regulates monosodium urate crystal-induced gouty inflammation.
- BiologyPharmacological research
The Pathognomic Radiologic Features of Gout in the Fingers and Review of the Literature, Including the Latest Drug Therapy
A patient is presented who was seen in the outpatient department with a first episode of tophaceous gout in the finger, an infrequently seen condition that mostly affects older men with long-term gout.
Treatment of asymptomatic hyperuricemia complicated by renal damage: a controversial issue
- MedicineInternational Urology and Nephrology
Further experimental studies are needed to determine the starting threshold and target value of asymptomatic HUA complicated by renal damage, and confirmation of the benefits of urate-lowering therapy for kidneys requires studies with larger samples and high-quality RCTs.