Gossamer - a resource-efficient de novo assembler

@article{Conway2012GossamerA,
  title={Gossamer - a resource-efficient de novo assembler},
  author={Thomas C. Conway and Jeremy Wazny and Andrew J. Bromage and Justin Zobel and Bryan Beresford-Smith},
  journal={Bioinformatics},
  year={2012},
  volume={28 14},
  pages={1937-8}
}
MOTIVATION The de novo assembly of short read high-throughput sequencing data poses significant computational challenges. The volume of data is huge; the reads are tiny compared to the underlying sequence, and there are significant numbers of sequencing errors. There are numerous software packages that allow users to assemble short reads, but most are either limited to relatively small genomes (e.g. bacteria) or require large computing infrastructure or employ greedy algorithms and thus often… CONTINUE READING

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