Goose lysozyme structure: an evolutionary link between hen and bacteriophage lysozymes?

@article{Gruetter1983GooseLS,
  title={Goose lysozyme structure: an evolutionary link between hen and bacteriophage lysozymes?},
  author={Markus G. Gruetter and Larry H. Weaver and Brian W. Matthews},
  journal={Nature},
  year={1983},
  volume={303},
  pages={828-831}
}
During evolution, the amino acid sequence of a protein is much more variable and changes more rapidly than its tertiary struc ture. Given sufficient time, the amino acid sequences of proteins derived from a common precursor may alter to the point that they are no longer demonstrably homologous. The ability to make meaningful comparisons between such distantly related proteins must therefore come primarily from structural homology, and only secondarily (if at all) from sequence homology1. On the… CONTINUE READING