Goodpasture antigen of the glomerular basement membrane: localization to noncollagenous regions of type IV collagen.

@article{Wieslander1984GoodpastureAO,
  title={Goodpasture antigen of the glomerular basement membrane: localization to noncollagenous regions of type IV collagen.},
  author={J{\"o}rgen Wieslander and Johnny Barr and Ralph J. Butkowski and Sally J Edwards and Per Bygren and Dick Heineg{\aa}rd and Billy G Hudson},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1984},
  volume={81 12},
  pages={3838-42}
}
The glomerular basement membrane antigen in Goodpasture syndrome is a collagenase-resistant molecule with a monomer molecular weight of about 26,000. Type IV collagen isolated from glomerular basement membrane contains collagenase-resistant sequences within its structure. Polyacrylamide gel electrophoresis, enzyme-linked immunosorbent assay, and chemical analysis were used to demonstrate that the collagenase-resistant sequences of type IV collagen contain Goodpasture antigen. 

Citations

Publications citing this paper.
Showing 1-10 of 44 extracted citations

Similar Papers

Loading similar papers…