Gonadotropin-releasing hormone receptors.

  title={Gonadotropin-releasing hormone receptors.},
  author={Robert Peter Millar and Zhi-Liang Lu and Adam J. Pawson and Colleen A. Flanagan and Kevin A Morgan and Stuart Maudsley},
  journal={Endocrine reviews},
  volume={25 2},
GnRH and its analogs are used extensively for the treatment of hormone-dependent diseases and assisted reproductive techniques. They also have potential as novel contraceptives in men and women. A thorough delineation of the molecular mechanisms involved in ligand binding, receptor activation, and intracellular signal transduction is kernel to understanding disease processes and the development of specific interventions. Twenty-three structural variants of GnRH have been identified in… CONTINUE READING
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