Gonadotropin-releasing hormone agonists and the skeleton.

  title={Gonadotropin-releasing hormone agonists and the skeleton.},
  author={Ignac Fogelman},
  journal={Fertility and sterility},
  volume={57 4},
OBJECTIVE To review and evaluate published studies that have assessed the effect on the skeleton of treatment with gonadotropin-releasing hormone agonists (GnRH-a). The effects on bone biochemistry and bone density are presented. DATA IDENTIFICATION Major studies reporting on bone and GnRH-a use were identified through Excerpta Medica and Medline searches. STUDY SELECTION Those that have reported on GnRH-a treatment in patients where data relating to skeletal metabolism or bone density were… CONTINUE READING