Gonadotropin releasing hormone agonists: Expanding vistas

@inproceedings{Magon2011GonadotropinRH,
  title={Gonadotropin releasing hormone agonists: Expanding vistas},
  author={Navneet Magon},
  booktitle={Indian journal of endocrinology and metabolism},
  year={2011}
}
Gonadotropin-releasing hormone (GnRH) agonists are derived from native GnRH by amino acid substitution which yields the agonist resistant to degradation and increases its half-life. The hypogonadotropic hypogonadal state produced by GnRH agonists has been often dubbed as "pseudomenopause" or "medical oophorectomy," which are both misnomers. GnRH analogues (GnRH-a) work by temporarily "switching off" the ovaries. Ovaries can be "switched off" for the therapy and therapeutic trial of many… CONTINUE READING

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