Gonadotropin-releasing hormone (LH-RH) and human chorionic gonadotropin in the treatment of two boys with hypogonadotrophic hypogonadism.

Abstract

Two brothers, 16 and 14 years of age, with hypogonadotrophic hypogonadism and anosmia were treated with subcutaneous injections of 200 microng gonadotropin-releasing hormone at 8-hour intervals for 4 weeks. Serum FSH increased to the range of normal adult men, but serum LH and serum testosterone showed little change and no clinical signs of pubertal… (More)

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@article{Krabbe1977GonadotropinreleasingH, title={Gonadotropin-releasing hormone (LH-RH) and human chorionic gonadotropin in the treatment of two boys with hypogonadotrophic hypogonadism.}, author={Simon Krabbe and Niels Erik Skakkebaek}, journal={Acta paediatrica Scandinavica}, year={1977}, volume={66 3}, pages={361-5} }