Gonadotropin-Releasing Hormone Agonists During Chemotherapy for Preservation of Ovarian Function and Fertility in Premenopausal Patients With Early Breast Cancer: A Systematic Review and Meta-Analysis of Individual Patient-Level Data.

@article{Lambertini2018GonadotropinReleasingHA,
  title={Gonadotropin-Releasing Hormone Agonists During Chemotherapy for Preservation of Ovarian Function and Fertility in Premenopausal Patients With Early Breast Cancer: A Systematic Review and Meta-Analysis of Individual Patient-Level Data.},
  author={Matteo Lambertini and Halle C. F. Moore and Robert C. F. Leonard and Sibylle Loibl and Pamela N. Munster and Marco Bruzzone and Luca Boni and J. Marshall Unger and Richard A. Anderson and Keyur Mehta and Susan Minton and Francesca Poggio and Kathy S. Albain and Douglas James Alexander Adamson and Bernd Gerber and Amy Cripps and Gianfilippo Bertelli and Sabine Seiler and Marcello Ceppi and Ann H Partridge and Lucia Del Mastro},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={2018},
  volume={36 19},
  pages={
          1981-1990
        }
}
Purpose The role of temporary ovarian suppression with gonadotropin-releasing hormone agonists (GnRHa) during chemotherapy as a strategy to preserve ovarian function and fertility in premenopausal women remains controversial. This systematic review and meta-analysis using individual patient-level data was conducted to better assess the efficacy and safety of this strategy in patients with early breast cancer. Methods The trials in which premenopausal women with early breast cancer were randomly… CONTINUE READING

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CMAR_A_204069 4273..4282

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CITES BACKGROUND
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Young Women with Breast Cancer: Fertility Preservation Options and Management of Pregnancy-Associated Breast Cancer

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CITES RESULTS & BACKGROUND
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