Gonadal transactivation of STARD1, CYP11A1 and HSD3B.

  title={Gonadal transactivation of STARD1, CYP11A1 and HSD3B.},
  author={Steven R. King and Holly A LaVoie},
  journal={Frontiers in bioscience},
The steroidogenic acute regulatory protein, cytochrome P450 cholesterol side-chain cleavage enzyme and specific 3beta-hydroxysteroid dehydrogenase/delta5-delta4 isomerases initiate the essential process of steroidogenesis in the gonads. Testicular and ovarian expression of their respective genes, STARD1, CYP11A1 and gonadal HSD3B, is primarily controlled by gonadotropins with contributions by various growth factors. Gonadotropins through their receptors switch on cyclic AMP signaling pathways… CONTINUE READING