Gonadal steroids influence serum somatomedin-C concentrations in prepubertal female rhesus monkey.

Abstract

The present study examined the influence of estradiol (E2) and androstenedione (delta 4) on the regulation of GH and somatomedin-C (Sm-C) secretion in prepubertal female rhesus monkeys. Ovariectomized animals (n = 9) received empty capsules (0) or capsules filled with E2 or delta 4 in successive 2-week treatment blocks as follows: 0, E2, E2 plus delta 4, 0… (More)

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