• DOI:10.1530/EJE.1.01886
Corpus ID: 27528976

Gonadal dysfunction in systemic diseases.

@article{Karagiannis2005GonadalDI,
  title={Gonadal dysfunction in systemic diseases.},
  author={A. Karagiannis and F. Harsoulis},
  journal={European journal of endocrinology},
  year={2005},
  volume={152 4},
  pages={
          501-13
        }
}

A. Karagiannis, F. Harsoulis

Published 2005

Biology, Medicine

European journal of endocrinology

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Gonadal function is significantly affected in many acute and chronic systemic diseases. As the function of the testes and the ovaries is determined by the integrity of the hypothalamic-pituitary-gonadal axis, it is obvious that a systemic disease may affect one or more levels of the axis in such a manner that the gonadal dysfunction may have various clinical and laboratory manifestations. In this brief review, the most common disturbances seen in the main systemic diseases will be discussed.