Gonadal dysfunction in adult male patients with thalassemia major: an update for clinicians caring for thalassemia.

Abstract

INTRODUCTION Hypogonadism is the most frequently reported endocrine complication, affecting 40%-80% of thalassemia major (TM) patients. The prevalence and severity of hypogonadism in TM varies among studies, depending on patients' age, genotype, transfusion frequency and starting age and efficiency of iron chelation. Areas covered: The diagnosis requires… (More)
DOI: 10.1080/17474086.2017.1398080

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