Gonadal cell apoptosis: hormone-regulated cell demise.

@article{Billig1996GonadalCA,
  title={Gonadal cell apoptosis: hormone-regulated cell demise.},
  author={H{\aa}kan Billig and S Y Chun and K M Eisenhauer and Aaron J Hsueh},
  journal={Human reproduction update},
  year={1996},
  volume={2 2},
  pages={103-17}
}
It has become evident that apoptosis, an active form of cell 'suicide', plays an important role in the normal function of all tissues. A balance of cell proliferation and apoptosis is maintained in a healthy individual and any imbalance of the two processes could lead to pathological changes. In both sexes, massive apoptosis accounts for the demise of a majority of gonadal cells (ovarian granulosa cells and male germ cells) during reproductive life. Recent studies have indicated the important… CONTINUE READING

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factors in the ovary ( oestrogens , insulin - like growth factor I , epidermal growth factor , basic fibroblast growth factor , interleukin-1 beta , nitric oxide , etc . ) and testis ( androgens ) have been shown to act in concert with the gonadotrophins .
factors in the ovary ( oestrogens , insulin - like growth factor I , epidermal growth factor , basic fibroblast growth factor , interleukin-1 beta , nitric oxide , etc . ) and testis ( androgens ) have been shown to act in concert with the gonadotrophins .
EstrogensNo subtypeOvary
factors in the ovary ( oestrogens , insulin - like growth factor I , epidermal growth factor , basic fibroblast growth factor , interleukin-1 beta , nitric oxide , etc . ) and testis ( androgens ) have been shown to act in concert with the gonadotrophins .
In both sexes , massive apoptosis accounts for the demise of a majority of gonadal cells ( ovarian granulosa cells and male germ cells ) during reproductive life .
In both sexes , massive apoptosis accounts for the demise of a majority of gonadal cells ( ovarian granulosa cells and male germ cells ) during reproductive life .
In both sexes , massive apoptosis accounts for the demise of a majority of gonadal cells ( ovarian granulosa cells and male germ cells ) during reproductive life .
In both sexes , massive apoptosis accounts for the demise of a majority of gonadal cells ( ovarian granulosa cells and male germ cells ) during reproductive life .
Gonadal structureIs primary anatomic site of diseaseGonadal Dysgenesis, 46,XY
Understanding of the hormonal and cellular mechanisms responsible for gonadal cell apoptosis will provide new approaches for the treatment of gonadal degenerative conditions such as premature ovarian failure and cryptorchidism , as well as for the design of new contraceptive approaches .
Gonadal structureIs associated anatomic site ofGonadal Dysgenesis, 46,XY
Understanding of the hormonal and cellular mechanisms responsible for gonadal cell apoptosis will provide new approaches for the treatment of gonadal degenerative conditions such as premature ovarian failure and cryptorchidism , as well as for the design of new contraceptive approaches .
factors in the ovary ( oestrogens , insulin - like growth factor I , epidermal growth factor , basic fibroblast growth factor , interleukin-1 beta , nitric oxide , etc . ) and testis ( androgens ) have been shown to act in concert with the gonadotrophins .
factors in the ovary ( oestrogens , insulin - like growth factor I , epidermal growth factor , basic fibroblast growth factor , interleukin-1 beta , nitric oxide , etc . ) and testis ( androgens ) have been shown to act in concert with the gonadotrophins .
OvaryNo subtypeEstrogens
factors in the ovary ( oestrogens , insulin - like growth factor I , epidermal growth factor , basic fibroblast growth factor , interleukin-1 beta , nitric oxide , etc . ) and testis ( androgens ) have been shown to act in concert with the gonadotrophins .
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