Gonadal Steroids Are Capable of Acting within the Hypothaiamus to Modulate Somatostatin (ss) Gene Expression in Pubertal Aged Rats

Abstract

Due to the highly complex nature of neuroendocrine-target organ “feedback” relationships, the primary site(s) at which gonadal steroids exert effects on the GH axis remain largely unknown. Therefore, we sought to test the hypotheses that testosterone (T) and estrudiol (E2) can exert direct cell-specific regulatory effects in vivo on hypothalamic neurons… (More)
DOI: 10.1203/00006450-199305001-00265

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