Golgi twins in late mitosis revealed by genetically encoded tags for live cell imaging and correlated electron microscopy.

@article{Gaietta2006GolgiTI,
  title={Golgi twins in late mitosis revealed by genetically encoded tags for live cell imaging and correlated electron microscopy.},
  author={Guido M. Gaietta and Ben N G Giepmans and Thomas J. Deerinck and William B. Smith and Lucy Ngan and Juan A. Sanchis Llopis and Stephen R Adams and Roger Tsien and Mark H. Ellisman},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2006},
  volume={103 47},
  pages={17777-82}
}
Combinations of molecular tags visible in light and electron microscopes become particularly advantageous in the analysis of dynamic cellular components like the Golgi apparatus. This organelle disassembles at the onset of mitosis and, after a sequence of poorly understood events, reassembles after cytokinesis. The precise location of Golgi membranes and resident proteins during mitosis remains unclear, partly due to limitations of molecular markers and the resolution of light microscopy. We… CONTINUE READING

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