Goldenrod – a classical exponent in the urological phytotherapy

  title={Goldenrod – a classical exponent in the urological phytotherapy},
  author={Matthias F. Melzig},
  journal={Wiener Medizinische Wochenschrift},
  • M. Melzig
  • Published 1 November 2004
  • Medicine
  • Wiener Medizinische Wochenschrift
SummaryHerbal remedies based on goldenrod (Solidago virgaurea L.) have been well-tried for centuries in the treatment of urinary tract diseases. Investigations in molecular pharmacology could show new mechanisms responsible for the biological effect of natural product from goldenrod extracts. The use of such herbal preparations with a rather complex action spectrum (anti-inflammatory, antimicrobial, diuretic, antispasmodic, analgesic) is especially recommended for treatment of infections and… 

Solidago virgaurea L.: A Review of Its Ethnomedicinal Uses, Phytochemistry, and Pharmacological Activities

The aerial parts of European goldenrod have long been used for urinary tract conditions and as an anti-inflammatory agent in the traditional medicine of different peoples and need more confirmation in both non-clinical models and clinical trials.

Herbal Resources with Antiurolithiatic Effects: A Review

The potential of medicinal plants in the treatment of urinary stone is explained and series of other traditional plants available and have been scientifically assessed for their antiurolithiatic activity are explained.

Herbal medicines in the management of urolithiasis: alternative or complementary?

In spite of substantial progress in the study of the biological and physical manifestations of kidney stones, there is no satisfactory drug to use in clinical therapy and the potential usefulness of herbal medicines in the management of urolithiasis is critically evaluated.

Herbal Drug Interactions

This chapter presents interactions of herbal medicines with other medicines (herbal or non-herbal) and suggests that it becomes important to keep an eye on the use of combination herbal therapy in order to avoid serious results because of interactions with each other.

Determination of bioactive compounds with benefic potential on health in several medicinal plants

Several bioactive compounds from plants like Chelidonium majus, Equisetum arvense and Hypericum perforatum are well known for their potential benefic effects on human and animal health. However, few

Chemical characteristics of European goldenrod (Solidago virgaurea L. subsp. virgaurea) from natural sites in central and eastern Poland.

In Poland European goldenrod grows all over the country. The raw material of this species is herb characterised by diuretic, detoxifying, anti-inflammatory, and bile se- cretion enhancing properties.

The anti‐inflammatory modulatory role of Solidago chilensis Meyen in the murine model of the air pouch

Results indicate that Solidago chilensis has a significant anti‐inflammatory action on acute inflammatory responses and that its inhibitory activity may be due not only to the inhibition of pro‐inflammatory mediators, but also to the inhibited of leucocyte infiltration.

Assessment of flavonoids and phenolic compound accumulation in invasive Solidago canadensis L. in Slovakia

The study of S. canadensis, growing in Slovakia, shows the promising potential that can be evaluated as an effective antioxidant and antimicrobial agent in herbal medicines.

Antibacterial and antimutagenic activity of extracts aboveground parts of three Solidago species: Solidago virgaurea L., Solidago canadensis L. and Solidago gigantea Ait.

It was found that alcohol extracts had slightly stronger antibacterial properties compared with lipophilic ones, whereas ethanolic extracts, in the applied range of concentrations, did not show antimutagenic activity.



Botanical medicines for the urinary tract

The antinephrotoxic botanicals Rheumpalmatum (Chinese rhubarb) root and Lespedezacapitata (round-head lespedeza) herb are surveyed, followed by herbs for symptoms of benign prostatic hyperplasia, most notably Serenoarepens (saw palmetto) fruit, Urticadioica root, and Prunusafricana (pygeum) bark.

Anti-inflammatory, spasmolytic and diuretic effects of a commercially available Solidago gigantea Herb. extract.

The evaluation of a commercially available Solidago gigantea Herb. extract (Urol mono) revealed pronounced anti-inflammatory properties in the rat with respect to a reduction of the

[Anti-inflammatory, analgesic and antipyretic effect of various plant extracts and their combinations in an animal model].

The phytotherapeutic preparation, containing three individual plant extracts produced dose-dependent antiinflammatory, analgesic and antipyretic effects which were similar to those of the reference substances salicyl alcohol and indometacin.

Antineoplastic Activity of Solidago virgaurea on Prostatic Tumor Cells in an SCID Mouse Model

During the course of screening for antineoplastic activities in various herbal plants, it was found that the extract of S. virgaurea exhibits strong cytotoxic activities on various tumor cell lines, which is effective on human prostate, breast, melanoma, and small cell lung carcinoma.

Pharmacokinetics of salicin after oral administration of a standardised willow bark extract

Willow bark extract in the current therapeutic dose leads to much lower serum salicylate levels than observed after analgesic doses of synthetic Salicylates, and the formation of salicylic acid alone is unlikely to explain analgesic or anti-rheumatic effects of willow bark.

Study of the anti-inflammatory activity of Populus tremula, Solidago virgaurea and Fraxinus excelsior.

Aqueous/alcoholic extracts of Populus tremula, Solidago virgaurea and Fraxinus excelsior (components of Phytodolor N) were tested individually and in 3 different combinations for anti-inflammatory

Herbal remedies of Solidago--correlation of phytochemical characteristics and antioxidative properties.

Inhibition of dihydrofolate reductase activity by alcoholic extracts from Fraxinus excelsior, Populus tremula and Solidago virgaurea.

Aqueous-ethanolic extracts of Fraxinus excelsior, Populus, tremula and Solidago virgaurea in a combination of 1: 3: 1 (v/v/v) are the components of the plant drug Phytodolor N (abbreviated as PD),

Immunomodulatory and antitumoral effects of triterpenoid saponins.

The mitogeneic and TNF alpha releasing virgaureasaponin E showed in vivo antitumoral effects in the allogeneic sarcoma 180 tumor model and in the syngeneic DBA/2-MC.SC-1 fibrosarcoma tumor model.

Cytotoxicity of triterpenoid saponins. Part 2: Relationships between the structures of glycosides of polygalacic acid and their activities against pathogenic Candida species.

Glycosides of polygalacic acid isolated from the aerial parts of Solidago virgaurea and produced by degradation of these genuine saponins were tested against humanpathogenic strains of Candida albicans, C. krusei and C. tropicalis using a micro-dilution assay and the antifungal action can be influenced the variation of the etherglycosidically bonded carbohydrate units at C-3.