GoldCLIP: Gel-omitted Ligation-dependent CLIP

  title={GoldCLIP: Gel-omitted Ligation-dependent CLIP},
  author={Jiaqi Gu and Ming Wang and Yang Yang and Ding Qiu and Yiqun Zhang and Jinbiao Ma and Yu Zhou and Gregory J. Hannon and Yang Yu},
  journal={Genomics, proteomics & bioinformatics},
  volume={16 2},
Protein-RNA interaction networks are essential to understand gene regulation control. Identifying binding sites of RNA-binding proteins (RBPs) by the UV-crosslinking and immunoprecipitation (CLIP) represents one of the most powerful methods to map protein-RNA interactions in vivo. However, the traditional CLIP protocol is technically challenging, which… CONTINUE READING