Gold thioglucose-induced hypothalamic damage, hyperphagia, and obesity: dependence on the adrenal gland.

Abstract

Previous studies from our laboratory suggested that adrenal hormones may participate, directly or indirectly, in the hypothalamic mechanism involved in the regulation of food intake. In the present studies, the effect of adrenalectomy on the development of gold thioglucose (GTG)-induced hyperphagia and obesity in mice was investigated. As expected, damage… (More)

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