Gold magnetic nanoparticle conjugate-based lateral flow assay for the detection of IgM class antibodies related to TORCH infections.

@article{Li2015GoldMN,
  title={Gold magnetic nanoparticle conjugate-based lateral flow assay for the detection of IgM class antibodies related to TORCH infections.},
  author={Xingxing Li and Qinlu Zhang and Peng Hou and Ming-wei Chen and Wenli Hui and A Vermorken and Zhiyi Luo and Hong Li and Qin Li and Yali Cui},
  journal={International journal of molecular medicine},
  year={2015},
  volume={36 5},
  pages={1319-26}
}
In this study, a lateral flow immunochromatographic assay (LFIA) system for the detection of immunoglobulin M (IgM) antibodies, related to TORCH [(T)oxoplasmosis, (O)ther agents, (R)ubella (also known as German Measles), (C)ytomegalovirus, and (H)erpes simplex virus infections], based on gold magnetic nanoparticles, was established. Following modification with poly(methacrylic acid), the gold magnetic nanoparticles conjugated with an anti‑human IgM antibody (μ‑chain specific) to construct a… CONTINUE READING
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