Gold‐Tip Electrodes—A New “Deep Lesion” Technology for Catheter Ablation? In Vitro Comparison of a Gold Alloy Versus Platinum–Iridium Tip Electrode Ablation Catheter

@article{Lewalter2005GoldTipEN,
  title={Gold‐Tip Electrodes—A New “Deep Lesion” Technology for Catheter Ablation? In Vitro Comparison of a Gold Alloy Versus Platinum–Iridium Tip Electrode Ablation Catheter},
  author={Thorsten Lewalter and Alexander Bitzen and Sabine WURTZ, Ph.D. and Robert BLUM, Ph.D. and Karsten SCHLODDER, Ph.D. and Alexander Yang and Lars Martin Lickfett and J{\"o}rg Otto Schwab and Jan Wilko Schrickel and Klaus Tiemann and Markus Linhart and Endre Zima and B{\'e}la Merkely and Berndt L{\"u}deritz},
  journal={Journal of Cardiovascular Electrophysiology},
  year={2005},
  volume={16}
}
Radiofrequency (RF) catheter ablation is widely used to induce focal myocardial necrosis using the effect of resistive heating through high‐frequency current delivery. It is current standard to limit the target tissue–electrode interface temperature to a maximum of 60–70°C to avoid char formation. Gold (Au) exhibits a thermal conductivity of nearly four times greater than platinum (Pt–Ir) (3.17 W/cm Kelvin vs 0.716 W/cm Kelvin), it was therefore hypothesized that RF ablation using a gold… 
In vitro comparison of platinum-iridium and gold tip electrodes: lesion depth in 4 mm, 8 mm, and irrigated-tip radiofrequency ablation catheters.
  • M. Linhart, H. Mollnau, +8 authors T. Lewalter
  • Medicine
    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology
  • 2009
TLDR
Both 4 and 8 mm not-irrigated gold tip catheters produced deeper lesions than the corresponding Pt tip catheter, and there was a trend towards less popping in the gold tip electrode.
New Polish prototypes of 4- and 8-mm-tip nonirrigated radiofrequency ablation catheters: an in vitro study
TLDR
It was shown that RF ablation catheters with the same length of the tip electrode created lesions of similar volume, irrespective of the manufacturer and despite showing distinct physical parameters during energy applications.
Effect of electrode thermal conductivity in cardiac radiofrequency catheter ablation: A computational modeling study
  • D. Schutt, E. Berjano, D. Haemmerich
  • Medicine
    International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group
  • 2009
TLDR
Computer modelling results show only minor increases in thermal lesion dimensions with electrode materials of higher thermal conductivity, and these observed differences likely do not provide a significant advantage during clinical procedures.
GOLDART—Gold Alloy Versus Platinum–Iridium Electrode for Ablation of AVNRT
TLDR
The current clinical trial was initiated to compare gold catheters with standard platinum–iridium (Pt–Ir) material and to analyze differences in the increase of power or temperature as a function of time during RF ablation.
Superiority of Gold versus Platinum Irrigated Tip Catheter Ablation of the Pulmonary Veins and the Cavotricuspid Isthmus: A Randomized Study Comparing Tip Temperatures and Cooling Flow Requirements
TLDR
This work sought to investigate the procedural parameters tip temperature, delivered power and cooling flow requirements of the irrigated gold tip catheter in comparison to the conventional irrigated platinum iridium tipCatheter in pulmonary vein isolation and cavotricuspid isthmus ablation.
Gold vs. platinum-iridium tip catheter for cavotricuspid isthmus ablation: the AURUM 8 study.
  • T. Lewalter, C. Weiss, +19 authors W. Bauer
  • Medicine, Biology
    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology
  • 2011
TLDR
Owing to a higher primary ablation success rate and reduced incidence of char/coagulum formation, gold may be preferred over Pt-Ir as electrode material for 8 mm tip catheters for CTI ablation.
Cavotricuspid Isthmus Ablation with Large‐Tip Gold Alloy Versus Platinum‐Iridium‐Tip Electrode Catheters
TLDR
The maximum voltage‐guided technique (MVGT) of cavotricuspid isthmus ablation using two 8‐mm tip catheters containing gold (group G) or platinum‐iridium (group PI) is tested.
First clinical experience of a dedicated irrigated-tip radiofrequency ablation catheter for the ablation of cavotricuspid isthmus-dependent atrial flutter
TLDR
In conclusion, acute and chronic efficacy of the irrigated Pt–Ir and gold-tip catheters were comparable, however, the dedicated catheter design was associated with decreased fluoroscopy duration.
...
1
2
3
4
...

References

SHOWING 1-9 OF 9 REFERENCES
Comparison of Gold Versus Platinum Electrodes on Myocardial Lesion Size Using Radiofrequency Energy
TLDR
It is concluded that deeper lesions should be able to be made when RF energy is delivered to a gold rather than platinum tip electrode, which has nearly four times the thermal conductivity as platinum.
Tissue Heating During Radiofrequency Catheter Ablation: A Thermodynamic Model and Observations in Isolated Perfused and Superfused Canine Right Ventricular Free Wall
TLDR
These data demonstrate that during radiofrequency catheter ablation, the radial temperature gradient is predictably hyperbolic and appears to be independent of intramyocardial perfusion if constant electrode temperature is maintained, and can accurately predict the ultimate size of radiofrequency‐induced lesions.
The Effect of Electrode Design on the Efficiency of Delivery of Radiofrequency Energy to Cardiac Tissue In Vitro
Four types of electrodes were studied with respect to efficiency of delivery of radiofrequency energy (HFE) and characteristics of the lesions produced in dog ventricular muscle in vitro. An
Is 8-mm More Effective Than 4-mm Tip Electrode Catheter for Ablation of Typical Atrial Flutter?
TLDR
A prospective, randomized study comparing 4- with 8-mm tip electrodes for radiofrequency linear ablation of typical atrial flutter and found the 8-MM electrode catheter achieved higher complete isthmus block rate and shorter procedure time than the 4-mm catheter.
Control of radiofrequency lesion size by power regulation.
TLDR
A gradual, controlled growth of the lesion can be obtained by a stepwise increase of the radiofrequency power level with ample exposure duration at each level to allow for stabilization.
Radio-frequency ablation as treatment for cardiac arrhythmias.
  • F. Morady
  • Medicine, Biology
    The New England journal of medicine
  • 1999
TLDR
The biophysics and results of radio-frequency catheter ablation and the clinical indications for its use are reviewed.
Factors influencing trans-catheter radiofrequency ablation of the myocardium
  • J Appl Cardiol
  • 1986
Factors influencing transcatheter radiofrequency ablation of the myocardium
  • J Appl Cardiol
  • 1986