Goal-directed Intraoperative Fluid Administration Reduces Length of Hospital Stay after Major Surgery

@article{Gan2002GoaldirectedIF,
  title={Goal-directed Intraoperative Fluid Administration Reduces Length of Hospital Stay after Major Surgery},
  author={Tong J. Gan and Andrew J Soppitt and M. Maroof and Habib E. El-Moalem and Kerri M. Robertson and Eugene W. Moretti and Peter D. Dwane and Peter s. A. Glass},
  journal={Anesthesiology},
  year={2002},
  volume={97},
  pages={820-826}
}
Background Intraoperative hypovolemia is common and is a potential cause of organ dysfunction, increased postoperative morbidity, length of hospital stay, and death. The objective of this prospective, randomized study was to assess the effect of goal-directed intraoperative fluid administration on length of postoperative hospital stay. Methods One hundred patients who were to undergo major elective surgery with an anticipated blood loss greater than 500 ml were randomly assigned to a control… 
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Implementation of fluid replacement guided by a dynamic preload variable (SVV) versus conventional static variables (CVP) is associated with lesser postoperative ICU stay and reduced fluid requirements in major abdominal surgery.
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In this study, fluid optimization guided by SVV during major abdominal surgery is associated with better intraoperative hemodynamic stability, decrease in serum lactate at the end of surgery and lower incidence of postoperative organ complications.
Conservative vs restrictive individualized goal-directed fluid replacement strategy in major abdominal surgery: A prospective randomized trial.
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Excessive fluid restriction increased the level of hypovolemia, leading to reduced Scvo₂ and thereby increased incidence of postoperative complications, and should be applied cautiously in surgical patients.
Perioperative Goal-Directed Hemodynamic Optimization Using Noninvasive Cardiac Output Monitoring in Major Abdominal Surgery: A Prospective, Randomized, Multicenter, Pragmatic Trial POEMAS Study (PeriOperative goal-directed thErapy in Major Abdominal Surgery)
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A pragmatic multi-center trial of goal-directed fluid management based on pulse pressure variation monitoring during high-risk surgery
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In high-risk surgeries, PPV-directed volume loading improved postoperative outcomes and decreased the postoperative hospital length of stay.
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