Goal-directed Intraoperative Fluid Administration Reduces Length of Hospital Stay after Major Surgery

@article{Gan2002GoaldirectedIF,
  title={Goal-directed Intraoperative Fluid Administration Reduces Length of Hospital Stay after Major Surgery},
  author={Tong J. Gan and Andrew J Soppitt and M. Maroof and Habib E. El-Moalem and Kerri M. Robertson and Eugene W. Moretti and Peter D. Dwane and Peter s. A. Glass},
  journal={Anesthesiology},
  year={2002},
  volume={97},
  pages={820-826}
}
Background Intraoperative hypovolemia is common and is a potential cause of organ dysfunction, increased postoperative morbidity, length of hospital stay, and death. The objective of this prospective, randomized study was to assess the effect of goal-directed intraoperative fluid administration on length of postoperative hospital stay. Methods One hundred patients who were to undergo major elective surgery with an anticipated blood loss greater than 500 ml were randomly assigned to a control… Expand

Paper Mentions

Interventional Clinical Trial
The purpose of the study is to test whether colloid-based goal-directed intraoperative fluid management leads to less perioperative morbidity compared to crystalloid-based goal-directed… Expand
ConditionsFluid Overload, Postoperative Complications
InterventionDrug
Interventional Clinical Trial
Despite Goal Directed Fluid Therapy (GDFT) has shown a reduction of hospitalization and overall complications in patients undergoing abdominal surgery, there is a need to address… Expand
ConditionsPostoperative Ileus
InterventionOther, Procedure
Interventional Clinical Trial
Goal directed volume therapy means that bolus doses of 150-250 ml colloid fluid is administered to the patient during contemporary measurement of the patients stroke volume. The… Expand
ConditionsPostoperative Complications
InterventionOther
Interventional Clinical Trial
The purpose of the study is to compare non-obese patients (BMI≤ 30 kg/m2)versus obese patients (BMI> 30 kg/m2) in regard of their respective needs for intraoperative fluid therapy… Expand
ConditionsObesity
InterventionOther
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TLDR
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Intraoperative GDFT did not improve clinical outcomes following major elective rectal surgery and was not shown to decrease complications and hospital length of stay in major colorectal surgery. Expand
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TLDR
Implementation of fluid replacement guided by a dynamic preload variable (SVV) versus conventional static variables (CVP) is associated with lesser postoperative ICU stay and reduced fluid requirements in major abdominal surgery. Expand
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TLDR
GDFT may not be of benefit to all elective patients undergoing major abdominal surgery, particularly those managed in an ERAS setting, particularly if managed in a traditional care setting. Expand
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TLDR
In this study, fluid optimization guided by SVV during major abdominal surgery is associated with better intraoperative hemodynamic stability, decrease in serum lactate at the end of surgery and lower incidence of postoperative organ complications. Expand
Conservative vs restrictive individualized goal-directed fluid replacement strategy in major abdominal surgery: A prospective randomized trial.
TLDR
Excessive fluid restriction increased the level of hypovolemia, leading to reduced Scvo₂ and thereby increased incidence of postoperative complications, and should be applied cautiously in surgical patients. Expand
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TLDR
The results of this study show that by using a goal-directed fluid therapy algorithm, the total amount of fluids administered can be reduced, as well as obtaining a lower incidence of post-operative complications. Expand
Perioperative Goal-Directed Hemodynamic Optimization Using Noninvasive Cardiac Output Monitoring in Major Abdominal Surgery: A Prospective, Randomized, Multicenter, Pragmatic Trial POEMAS Study (PeriOperative goal-directed thErapy in Major Abdominal Surgery)
TLDR
The results of this pragmatic study indicate that a perioperative hemodynamic protocol guided by a noninvasive cardiac output monitor was not associated with a decrease in the incidence of overall complications or length of stay in major abdominal surgery. Expand
A pragmatic multi-center trial of goal-directed fluid management based on pulse pressure variation monitoring during high-risk surgery
TLDR
In high-risk surgeries, PPV-directed volume loading improved postoperative outcomes and decreased the postoperative hospital length of stay. Expand
Effect of intraoperative fluid optimisation on renal function in patients undergoing emergency abdominal surgery: a randomised controlled pilot study (ISRCTN 11799696).
TLDR
Replacing the identified fluid deficit was not associated with a change in renal function and these results do not preclude that goal directed therapy using fluid alone may have an effect on renal function but they would suggest that the effect size of fluid optimisation alone on renalfunction is small. Expand
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