Gnotobiotic zebrafish reveal evolutionarily conserved responses to the gut microbiota.

  title={Gnotobiotic zebrafish reveal evolutionarily conserved responses to the gut microbiota.},
  author={John F Rawls and Buck S Samuel and Jeffrey I. Gordon},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={101 13},
Animals have developed the means for supporting complex and dynamic consortia of microorganisms during their life cycle. A transcendent view of vertebrate biology therefore requires an understanding of the contributions of these indigenous microbial communities to host development and adult physiology. These contributions are most obvious in the gut, where studies of gnotobiotic mice have disclosed that the microbiota affects a wide range of biological processes, including nutrient processing… CONTINUE READING
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