Glypican1/2/4/6 and sulfated glycosaminoglycans regulate the patterning of the primary body axis in the cnidarian Nematostella vectensis.

@article{Bause2016Glypican1246AS,
  title={Glypican1/2/4/6 and sulfated glycosaminoglycans regulate the patterning of the primary body axis in the cnidarian Nematostella vectensis.},
  author={M. Bause and Roddy van der Horst and F. Rentzsch},
  journal={Developmental biology},
  year={2016},
  volume={414 1},
  pages={
          108-20
        }
}
  • M. Bause, Roddy van der Horst, F. Rentzsch
  • Published 2016
  • Biology, Medicine
  • Developmental biology
  • Glypicans are members of the heparan sulfate (HS) subfamily of proteoglycans that can function in cell adhesion, cell crosstalk and as modulators of the major developmental signalling pathways in bilaterians. The evolutionary origin of these multiple functions is not well understood. In this study we investigate the role of glypicans in the embryonic and larval development of the sea anemone Nematostella vectensis, a member of the non-bilaterian clade Cnidaria. Nematostella has two glypican… CONTINUE READING
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