Glyphosate impairs male offspring reproductive development by disrupting gonadotropin expression

  title={Glyphosate impairs male offspring reproductive development by disrupting gonadotropin expression},
  author={M A Romano and Renata Marino Romano and Luciana Dalazen Santos and Patricia Wisniewski and Daniele Antonelo Campos and Paula Bargi de Souza and Priscila Viau and Maria Martha Bernardi and Maria Tereza Nunes and Cl{\'a}udio Alvarenga de Oliveira},
  journal={Archives of Toxicology},
Sexual differentiation in the brain takes place from late gestation to the early postnatal days. This is dependent on the conversion of circulating testosterone into estradiol by the enzyme aromatase. The glyphosate was shown to alter aromatase activity and decrease serum testosterone concentrations. Thus, the aim of this study was to investigate the effect of gestational maternal glyphosate exposure (50 mg/kg, NOAEL for reproductive toxicity) on the reproductive development of male offspring… CONTINUE READING
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