Glyoxylate metabolism is a key feature of the metabolic degradation of 1,4-dioxane by Pseudonocardia dioxanivorans strain CB1190.

@article{Grostern2012GlyoxylateMI,
  title={Glyoxylate metabolism is a key feature of the metabolic degradation of 1,4-dioxane by Pseudonocardia dioxanivorans strain CB1190.},
  author={Ariel Grostern and Christopher M. Sales and Wei-Qin Zhuang and Onur Erbilgin and Lisa Alvarez-Cohen},
  journal={Applied and environmental microbiology},
  year={2012},
  volume={78 9},
  pages={3298-308}
}
The groundwater contaminant 1,4-dioxane (dioxane) is transformed by several monooxygenase-expressing microorganisms, but only a few of these, including Pseudonocardia dioxanivorans strain CB1190, can metabolize the compound as a sole carbon and energy source. However, nothing is yet known about the genetic basis of dioxane metabolism. In this study, we used a microarray to study differential expression of genes in strain CB1190 grown on dioxane, glycolate (a previously identified intermediate… CONTINUE READING

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