Glyoxal‐Induced Premature Senescence in Human Fibroblasts

@article{Sejersen2007GlyoxalInducedPS,
  title={Glyoxal‐Induced Premature Senescence in Human Fibroblasts},
  author={H. Sejersen and S. Rattan},
  journal={Annals of the New York Academy of Sciences},
  year={2007},
  volume={1100}
}
Abstract:  Mild stress‐induced hormesis is an effective strategy to intervene in the aging process. Repeated exposure of human skin fibroblasts to 41°C heat shock for 1 h twice a week is an example of mild stress that has many hormetic effects, including improved resistance to other stressors. We are now developing an experimental model system of sugar‐induced premature senescence, which can be useful to test the hormetic and antiaging effects of other stresses. Our present studies show that… Expand
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