Glycosylphosphatidylinositol-anchored Proteases of Candida albicans Target Proteins Necessary for Both Cellular Processes and Host-Pathogen Interactions*

@article{Albrecht2006Glycosylphosphatidylinositolancho,
  title={Glycosylphosphatidylinositol-anchored Proteases of Candida albicans Target Proteins Necessary for Both Cellular Processes and Host-Pathogen Interactions*},
  author={A. Albrecht and A. Felk and I. Pichov{\'a} and J. Naglik and M. Schaller and P. de Groot and D. MacCallum and F. Odds and W. Schaefer and F. Klis and M. Monod and B. Hube},
  journal={Journal of Biological Chemistry},
  year={2006},
  volume={281},
  pages={688 - 694}
}
  • A. Albrecht, A. Felk, +9 authors B. Hube
  • Published 2006
  • Medicine, Psychology, Biology
  • Journal of Biological Chemistry
  • Intracellular and secreted proteases fulfill multiple functions in microorganisms. In pathogenic microorganisms extracellular proteases may be adapted to interactions with host cells. Here we describe two cell surface-associated aspartic proteases, Sap9 and Sap10, which have structural similarities to yapsins of Saccharomyces cerevisiae and are produced by the human pathogenic yeast Candida albicans. Sap9 and Sap10 are glycosylphosphatidylinositol-anchored and located in the cell membrane or… CONTINUE READING

    Figures, Tables, and Topics from this paper.

    Proteolytic Cleavage of Covalently Linked Cell Wall Proteins by Candida albicans Sap9 and Sap10
    73

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 51 REFERENCES
    Adhesion in Candida spp
    309