Glycosylation regulates Notch signalling

@article{Haines2003GlycosylationRN,
  title={Glycosylation regulates Notch signalling},
  author={N. Haines and K. Irvine},
  journal={Nature Reviews Molecular Cell Biology},
  year={2003},
  volume={4},
  pages={786-797}
}
Intracellular post-translational modifications such as phosphorylation and ubiquitylation have been well studied for their roles in regulating diverse signalling pathways, but we are only just beginning to understand how differential glycosylation is used to regulate intercellular signalling. Recent studies make clear that extracellular post-translational modifications, in the form of glycosylation, are essential for the Notch signalling pathway, and that differences in the extent of… Expand
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