Glycosylation of nail in diabetics: possible marker of long-term hyperglycemia.

  title={Glycosylation of nail in diabetics: possible marker of long-term hyperglycemia.},
  author={Ebubekir Bakan and Nuri Bakan},
  journal={Clinica chimica acta; international journal of clinical chemistry},
  volume={147 1},
Fingernail samples from 32 patients with diabetes mellitus and from 26 non-diabetics were analyzed in order to determine the protein glycosylation rate in nail. Nail glycosylation was assayed by the thiobarbituric acid reaction. Blood was taken from both diabetics and non-diabetics at the same time for measurement of hemoglobin glycosylation. In non-diabetics, the protein glycosylation in nail and glycosylated hemoglobin were found to be 8.35 +/- 2.7 nmol fructosamine/mg nail and 2.24 +/- 0.45… CONTINUE READING