Glycosylation of KEAP1 links nutrient sensing to redox stress signaling.


O-GlcNAcylation is an essential, nutrient-sensitive post-translational modification, but its biochemical and phenotypic effects remain incompletely understood. To address this question, we investigated the global transcriptional response to perturbations in O-GlcNAcylation. Unexpectedly, many transcriptional effects of O-GlcNAc transferase (OGT) inhibition… (More)
DOI: 10.15252/embj.201696113


Cite this paper

@article{Chen2017GlycosylationOK, title={Glycosylation of KEAP1 links nutrient sensing to redox stress signaling.}, author={Po-Han Chen and Timothy J. Smith and Jianli Wu and Priscila M. Fonseca - Siesser and Brittany J Bisnett and Farhan Raza Khan and Maxwell Hogue and Erik J. Soderblom and Flora Tang and Jeffrey R. Marks and Michael B. Major and Benjamin M Swarts and Michael Boyce and Jen-Tsan Chi}, journal={The EMBO journal}, year={2017}, volume={36 15}, pages={2233-2250} }