Glycosylation of Immunoglobulin G Associates With Clinical Features of Inflammatory Bowel Diseases.

@article{imurina2018GlycosylationOI,
  title={Glycosylation of Immunoglobulin G Associates With Clinical Features of Inflammatory Bowel Diseases.},
  author={Mirna {\vS}imurina and Noortje de Haan and Frano Vu{\vc}kovi{\'c} and N A Kennedy and Jerko {\vS}tambuk and David Falck and Irena Trbojevi{\'c}-Akma{\vc}i{\'c} and Florent Clerc and Genadij Razdorov and Anna Khon and Anna Latiano and Renata D'inc{\'a} and Silvio Danese and Stephan Raoul Targan and Carol J. Landers and Marla Cindy Dubinsky and Dermot P. B. McGovern and Vito Annese and Manfred Wuhrer and Gordan Lauc},
  journal={Gastroenterology},
  year={2018},
  volume={154 5},
  pages={
          1320-1333.e10
        }
}
BACKGROUND AND AIMS Causes of inflammatory bowel diseases are not well understood and the most prominent forms, Crohn's disease (CD) and ulcerative colitis (UC), are sometimes hard to distinguish. Glycosylation of IgG has been associated with CD and UC. IgG Fc-glycosylation affects IgG effector functions. We evaluated changes in IgG Fc-glycosylation associated with UC and CD, as well as with disease characteristics in different patient groups. METHODS We analyzed 3441 plasma samples obtained… CONTINUE READING

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Causes of inflammatory bowel diseases are not well understood and the most prominent forms , Crohn 's disease ( CD ) and ulcerative colitis ( UC ) , are sometimes hard to distinguish .
Causes of inflammatory bowel diseases are not well understood and the most prominent forms , Crohn 's disease ( CD ) and ulcerative colitis ( UC ) , are sometimes hard to distinguish .
Causes of inflammatory bowel diseases are not well understood and the most prominent forms , Crohn 's disease ( CD ) and ulcerative colitis ( UC ) , are sometimes hard to distinguish .
Causes of inflammatory bowel diseases are not well understood and the most prominent forms , Crohn 's disease ( CD ) and ulcerative colitis ( UC ) , are sometimes hard to distinguish .
Causes of inflammatory bowel diseases are not well understood and the most prominent forms , Crohn 's disease ( CD ) and ulcerative colitis ( UC ) , are sometimes hard to distinguish .
Causes of inflammatory bowel diseases are not well understood and the most prominent forms , Crohn 's disease ( CD ) and ulcerative colitis ( UC ) , are sometimes hard to distinguish .
Causes of inflammatory bowel diseases are not well understood and the most prominent forms , Crohn 's disease ( CD ) and ulcerative colitis ( UC ) , are sometimes hard to distinguish .
Causes of inflammatory bowel diseases are not well understood and the most prominent forms , Crohn 's disease ( CD ) and ulcerative colitis ( UC ) , are sometimes hard to distinguish .
Causes of inflammatory bowel diseases are not well understood and the most prominent forms , Crohn 's disease ( CD ) and ulcerative colitis ( UC ) , are sometimes hard to distinguish .
Causes of inflammatory bowel diseases are not well understood and the most prominent forms , Crohn 's disease ( CD ) and ulcerative colitis ( UC ) , are sometimes hard to distinguish .
Causes of inflammatory bowel diseases are not well understood and the most prominent forms , Crohn 's disease ( CD ) and ulcerative colitis ( UC ) , are sometimes hard to distinguish .
Causes of inflammatory bowel diseases are not well understood and the most prominent forms , Crohn 's disease ( CD ) and ulcerative colitis ( UC ) , are sometimes hard to distinguish .
Causes of inflammatory bowel diseases are not well understood and the most prominent forms , Crohn 's disease ( CD ) and ulcerative colitis ( UC ) , are sometimes hard to distinguish .
Causes of inflammatory bowel diseases are not well understood and the most prominent forms , Crohn 's disease ( CD ) and ulcerative colitis ( UC ) , are sometimes hard to distinguish .
Causes of inflammatory bowel diseases are not well understood and the most prominent forms , Crohn 's disease ( CD ) and ulcerative colitis ( UC ) , are sometimes hard to distinguish .
IntestinesIs associated anatomic site ofUlcerative Colitis
Causes of inflammatory bowel diseases are not well understood and the most prominent forms , Crohn 's disease ( CD ) and ulcerative colitis ( UC ) , are sometimes hard to distinguish .
IntestinesIs primary anatomic site of diseaseUlcerative Colitis
Causes of inflammatory bowel diseases are not well understood and the most prominent forms , Crohn 's disease ( CD ) and ulcerative colitis ( UC ) , are sometimes hard to distinguish .
Causes of inflammatory bowel diseases are not well understood and the most prominent forms , Crohn 's disease ( CD ) and ulcerative colitis ( UC ) , are sometimes hard to distinguish .
IntestinesIs primary anatomic site of diseaseCrohn Disease
Causes of inflammatory bowel diseases are not well understood and the most prominent forms , Crohn 's disease ( CD ) and ulcerative colitis ( UC ) , are sometimes hard to distinguish .
IntestinesIs associated anatomic site ofCrohn Disease
Causes of inflammatory bowel diseases are not well understood and the most prominent forms , Crohn 's disease ( CD ) and ulcerative colitis ( UC ) , are sometimes hard to distinguish .
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