Glycosylation in the control of selectin counter-receptor structure and function.

@article{Lowe2002GlycosylationIT,
  title={Glycosylation in the control of selectin counter-receptor structure and function.},
  author={John B. Lowe},
  journal={Immunological reviews},
  year={2002},
  volume={186},
  pages={
          19-36
        }
}
Leukocyte trafficking is characterized by sequential cell adhesion and activation events that deliver specific leukocyte subsets to distinct extravascular locations under different pathophysiological circumstances. E-, P- and/or L-selectin-dependent leukocyte-endothelial cell adhesive interactions contribute essentially to this process. Selectin counter-receptor activity on leukocyte and high endothelial venules is borne by specific glycoproteins whose ability to support adhesion requires… CONTINUE READING
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