Glycosylation Site for Chondroitin Sulfate on the Neural Part-time Proteoglycan, Neuroglycan C*

  title={Glycosylation Site for Chondroitin Sulfate on the Neural Part-time Proteoglycan, Neuroglycan C*},
  author={Sachiko Aono and Yoshihito Tokita and Takuya Shuo and Shinobu Yamauchi and Fumiko Matsui and Keiko Nakanishi and Kanako Hirano and Mamoru Sano and Atsuhiko Oohira},
  journal={Journal of Biological Chemistry},
  pages={46536 - 46541}
Neuroglycan C (NGC) is a membrane-spanning chondroitin sulfate (CS) proteoglycan that is expressed predominantly in the central nervous system (CNS). NGC dramatically changed its structure from a proteoglycan to a nonproteoglycan form with cerebellar development, whereas a small portion of NGC molecules existed in a nonproteoglycan form in the other areas of the mature CNS, suggesting that the CS glycosylation of NGC is developmentally regulated in the whole CNS. As primary cultured neurons and… 

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